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Ohio State University is stepping forward to fight antibiotic resistance and help prevent the next global health crisis. Researchers from the five colleges of Ohio State University collaborated through a "single health" approach to study this issue from the perspective of human, animal, and environmental health.
Bacterial infections that are usually treated with antibiotics are increasingly resistant to treatment, and as bacteria evolve faster than new therapies are developed, life-threatening diseases may appear.
Researchers at Oregon State University said that a key factor in the global antimicrobial resistance problem is the long-term overprescription of antibiotics for human and animal viral diseases, and the treatment of these diseases is ineffective.
Ohio State University’s Antimicrobial Management Program educates health care workers, veterinarians, students, and patients about the proper and optimal use of antibiotics in humans and animals. Experts at Ohio State University Wexner Medical Center are collaborating with colleagues in medicine, veterinary medicine, pharmacy, public health and food, and agriculture and environmental sciences through the Ohio State University Institute of Infectious Diseases to reduce antibiotic resistance.
The Food and Agriculture Organization of the United Nations has designated Ohio's IDI as one of the eight international reference centers for antimicrobial resistance in the world.
ASP works closely with clinicians on guidelines, policies, and prescription recommendations to determine the best antimicrobial treatment for infections, while considering cost, toxicity, and resistance development issues to ensure proper use.
Erica Reed, an infectious disease pharmacist at Ohio State University Wexner Medical Center, said: "The more cards you show to bacteria, the easier it is for them to practice bypassing the drug." We have seen patients with life-threatening infections, and we have almost no effective drugs to treat them."
Researchers at Ohio State University are studying multiple ways of spreading antibiotic-resistant bacteria, whether they are spread between humans and animals, or through waterways to livestock, and then may infect the food supply.
A discovery made by Ohio State University veterinary researchers nearly a decade ago led to changes in disinfection practices in environments ranging from hospital rooms to pig farms around the world. Researchers have determined the microorganisms that develop resistance to specific disinfectants and automatically develop resistance to multiple antibiotics.
"Whether it is in the river, wastewater treatment plant, veterinary clinic or medical center, they all play a role in the problem and all have potential contributions to the solution," said Professor and Department Chair Thomas Wittum. Veterinary preventive medicine.
In 2018, the School of Veterinary Medicine launched its own comprehensive antimicrobial management plan to help veterinarians and students confidently make informed decisions on antimicrobial use while providing the best care for animal patients. Next, experts hope to modify the procedure to apply it to private veterinary clinics across the state.
Reid said that the COVID-19 pandemic highlights the importance of properly managing infections, and he believes that a management network needs to be established among global partners to help prevent dangerous future infections.
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